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Cytotoxic Effect of Immunotoxin Containing The Truncated Form of Pseudomonas Exotoxin A and Anti-VEGFR2 on HUVEC and MCF-7 Cell Lines

OBJECTIVE: Immunotoxins (ITs) have been developed for the treatment of cancer, and comprise of antibodies linked to toxins. Also vascular endothelial growth factor (VEGF) plays a key role in tumor angiogenesis, and the blockade of VEGF receptor-2 (VEGFR2) inhibits angiogenesis and tumor growth. The...

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Detalles Bibliográficos
Autores principales:	Safari, Elahe, Zavaran Hosseini, Ahmad, Hassan, Zuhair, Khajeh, Khosro, Ardestani, Mehdi Shafiee, Baradaran, Behzad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royan Institute 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072084/ https://www.ncbi.nlm.nih.gov/pubmed/24567937

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