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Nestin(+) Tissue-Resident Multipotent Stem Cells Contribute to Tumor Progression by Differentiating into Pericytes and Smooth Muscle Cells Resulting in Blood Vessel Remodeling

Tumor vessels with resistance to anti-angiogenic therapy are characterized by the normalization of the vascular structures through integration of mature pericytes and smooth muscle cells (SMC) into the vessel wall, a process termed vessel stabilization. Unfortunately, stabilization-associated vascul...

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Detalles Bibliográficos
Autores principales: Klein, Diana, Meissner, Nicole, Kleff, Veronika, Jastrow, Holger, Yamaguchi, Masahiro, Ergün, Süleyman, Jendrossek, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072089/
https://www.ncbi.nlm.nih.gov/pubmed/25019063
http://dx.doi.org/10.3389/fonc.2014.00169