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Geldanamycin attenuates 3-nitropropionic acid-induced apoptosis and JNK activation through the expression of HSP 70 in striatal cells

Although selective striatal cell death is a characteristic hallmark in the pathogenesis of Huntington’s disease (HD), the underlying mechanism of striatal susceptibility remains to be clarified. Heat shock proteins (HSPs) have been reported to suppress the aggregate formation of mutant huntingtin an...

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Detalles Bibliográficos
Autores principales:	CHOI, YONG-JOON, KIM, NAM HO, LIM, MAN SUP, LEE, HEE JAE, KIM, SUNG SOO, CHUN, WANJOO
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072345/ https://www.ncbi.nlm.nih.gov/pubmed/24756698 http://dx.doi.org/10.3892/ijmm.2014.1747

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