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Biochemical Characterization of the Phosphatase Domain of the Tumor Suppressor PH Domain Leucine-Rich Repeat Protein Phosphatase

[Image: see text] PH domain leucine-rich repeat protein phosphatase (PHLPP) directly dephosphorylates and inactivates Akt and protein kinase C and is therefore a prime target for pharmacological intervention of two key signaling pathways, the phosphatidylinositol 3-kinase and diacylglycerol signalin...

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Detalles Bibliográficos
Autores principales:	Sierecki, Emma, Newton, Alexandra C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072346/ https://www.ncbi.nlm.nih.gov/pubmed/24892992 http://dx.doi.org/10.1021/bi500428j

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