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Variability in Dengue Titer Estimates from Plaque Reduction Neutralization Tests Poses a Challenge to Epidemiological Studies and Vaccine Development

BACKGROUND: Accurate determination of neutralization antibody titers supports epidemiological studies of dengue virus transmission and vaccine trials. Neutralization titers measured using the plaque reduction neutralization test (PRNT) are believed to provide a key measure of immunity to dengue viru...

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Detalles Bibliográficos
Autores principales: Salje, Henrik, Rodríguez-Barraquer, Isabel, Rainwater-Lovett, Kaitlin, Nisalak, Ananda, Thaisomboonsuk, Butsaya, Thomas, Stephen J., Fernandez, Stefan, Jarman, Richard G., Yoon, In-Kyu, Cummings, Derek A. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072537/
https://www.ncbi.nlm.nih.gov/pubmed/24967885
http://dx.doi.org/10.1371/journal.pntd.0002952