Cargando…

Variability in Dengue Titer Estimates from Plaque Reduction Neutralization Tests Poses a Challenge to Epidemiological Studies and Vaccine Development

BACKGROUND: Accurate determination of neutralization antibody titers supports epidemiological studies of dengue virus transmission and vaccine trials. Neutralization titers measured using the plaque reduction neutralization test (PRNT) are believed to provide a key measure of immunity to dengue viru...

Descripción completa

Detalles Bibliográficos
Autores principales:	Salje, Henrik, Rodríguez-Barraquer, Isabel, Rainwater-Lovett, Kaitlin, Nisalak, Ananda, Thaisomboonsuk, Butsaya, Thomas, Stephen J., Fernandez, Stefan, Jarman, Richard G., Yoon, In-Kyu, Cummings, Derek A. T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072537/ https://www.ncbi.nlm.nih.gov/pubmed/24967885 http://dx.doi.org/10.1371/journal.pntd.0002952

Ejemplares similares

Variation in dengue virus plaque reduction neutralization testing: systematic review and pooled analysis
por: Rainwater-Lovett, Kaitlin, et al.
Publicado: (2012)

Reconstruction of antibody dynamics and infection histories to evaluate dengue risk
por: Salje, Henrik, et al.
Publicado: (2018)

Evaluation of a Dengue NS1 Antigen Detection Assay Sensitivity and Specificity for the Diagnosis of Acute Dengue Virus Infection
por: Hermann, Laura L., et al.
Publicado: (2014)

Neutralizing Dengue Antibody in Pregnant Thai Women and Cord Blood
por: Khamim, Kriangsak, et al.
Publicado: (2015)

Dengue Virus Neutralizing Antibody Levels Associated with Protection from Infection in Thai Cluster Studies
por: Buddhari, Darunee, et al.
Publicado: (2014)

Viridot: An automated virus plaque (immunofocus) counter for the measurement of serological neutralizing responses with application to dengue virus
por: Katzelnick, Leah C., et al.
Publicado: (2018)

Epidemiology of Infant Dengue Cases Illuminates Serotype-Specificity in the Interaction between Immunity and Disease, and Changes in Transmission Dynamics
por: Clapham, Hannah, et al.
Publicado: (2015)

Opportunities for improved surveillance and control of dengue from age-specific case data
por: Rodriguez-Barraquer, Isabel, et al.
Publicado: (2019)

Beneath the surface: Amino acid variation underlying two decades of dengue virus antigenic dynamics in Bangkok, Thailand
por: Huang, Angkana T., et al.
Publicado: (2022)

Synchrony of Dengue Incidence in Ho Chi Minh City and Bangkok
por: Hoang Quoc, Cuong, et al.
Publicado: (2016)

Reconstruction of 60 Years of Chikungunya Epidemiology in the Philippines Demonstrates Episodic and Focal Transmission
por: Salje, Henrik, et al.
Publicado: (2016)

Maternally derived antibody titer dynamics and risk of hospitalized infant dengue disease
por: O’Driscoll, Megan, et al.
Publicado: (2023)

Antigenic diversity and dengue disease risk
por: Wang, Lin, et al.
Publicado: (2023)

High Rate of Subclinical Chikungunya Virus Infection and Association of Neutralizing Antibody with Protection in a Prospective Cohort in The Philippines
por: Yoon, In-Kyu, et al.
Publicado: (2015)

Precision Tracing of Household Dengue Spread Using Inter- and Intra-Host Viral Variation Data, Kamphaeng Phet, Thailand
por: Berry, Irina Maljkovic, et al.
Publicado: (2021)

Immunogenic Properties of a BCG Adjuvanted Chitosan Nanoparticle-Based Dengue Vaccine in Human Dendritic Cells
por: Hunsawong, Taweewun, et al.
Publicado: (2015)

Differential Susceptibility of Two Field Aedes aegypti Populations to a Low Infectious Dose of Dengue Virus
por: Pongsiri, Arissara, et al.
Publicado: (2014)

Kinetics of Chikungunya Infections during an Outbreak in Southern Thailand, 2008–2009
por: Chusri, Sarunyou, et al.
Publicado: (2014)

Frequent In-Migration and Highly Focal Transmission of Dengue Viruses among Children in Kamphaeng Phet, Thailand
por: Rabaa, Maia A., et al.
Publicado: (2013)

Reconstructing unseen transmission events to infer dengue dynamics from viral sequences
por: Salje, Henrik, et al.
Publicado: (2021)

Viral Epidemiology: Tracking Viruses with Smartphones and Social Media
por: Rainwater-Lovett, Kaitlin, et al.
Publicado: (2016)

No evidence for local adaptation of dengue viruses to mosquito vector populations in Thailand
por: Fansiri, Thanyalak, et al.
Publicado: (2016)

Genetic specificity and potential for local adaptation between dengue viruses and mosquito vectors
por: Lambrechts, Louis, et al.
Publicado: (2009)

The Spatial Dynamics of Dengue Virus in Kamphaeng Phet, Thailand
por: Bhoomiboonchoo, Piraya, et al.
Publicado: (2014)

Incidence of Dengue Virus Infection in Adults and Children in a Prospective Longitudinal Cohort in the Philippines
por: Alera, Maria Theresa, et al.
Publicado: (2016)

The Impact of the Demographic Transition on Dengue in Thailand: Insights from a Statistical Analysis and Mathematical Modeling
por: Cummings, Derek A. T., et al.
Publicado: (2009)

Genetic Mapping of Specific Interactions between Aedes aegypti Mosquitoes and Dengue Viruses
por: Fansiri, Thanyalak, et al.
Publicado: (2013)

Comparison of real-time SYBR green dengue assay with real-time taqman RT-PCR dengue assay and the conventional nested PCR for diagnosis of primary and secondary dengue infection
por: Paudel, Damodar, et al.
Publicado: (2011)

Detection of Zika Virus Infection in Thailand, 2012–2014
por: Buathong, Rome, et al.
Publicado: (2015)

Polytopic vaccination with a live-attenuated dengue vaccine enhances B-cell and T-cell activation, but not neutralizing antibodies
por: Hunsawong, Taweewun, et al.
Publicado: (2017)

Diversity and Origin of Dengue Virus Serotypes 1, 2, and 3, Bhutan
por: Dorji, Tandin, et al.
Publicado: (2009)

Epidemiological and Molecular Characterization of Dengue Virus Circulating in Bhutan, 2013-2014
por: Zangmo, Sangay, et al.
Publicado: (2015)

Correlation between reported dengue illness history and seropositivity in rural Thailand
por: Buddhari, Darunee, et al.
Publicado: (2021)

Correlation between herpes simplex virus neutralizing antibody titers determined by ELVIS cell and traditional plaque reduction assays
por: Blevins, Tamara P., et al.
Publicado: (2019)

Associations of human leukocyte antigen with neutralizing antibody titers in a tetravalent dengue vaccine phase 2 efficacy trial in Thailand
por: Thomas, Rasmi, et al.
Publicado: (2022)

Determinants of Inapparent and Symptomatic Dengue Infection in a Prospective Study of Primary School Children in Kamphaeng Phet, Thailand
por: Endy, Timothy P., et al.
Publicado: (2011)

Challenges in the Interpretation of Dengue Vaccine Trial Results
por: Rodriguez-Barraquer, Isabel, et al.
Publicado: (2013)

Optimization and Validation of a Plaque Reduction Neutralization Test for the Detection of Neutralizing Antibodies to Four Serotypes of Dengue Virus Used in Support of Dengue Vaccine Development
por: Timiryasova, Tatyana M., et al.
Publicado: (2013)

Resolution of a Chikungunya Outbreak in a Prospective Cohort, Cebu, Philippines, 2012–2014
por: Srikiatkhachorn, Anon, et al.
Publicado: (2016)

An Innovative, Prospective, Hybrid Cohort-Cluster Study Design to Characterize Dengue Virus Transmission in Multigenerational Households in Kamphaeng Phet, Thailand
por: Anderson, Kathryn B, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6oetlbi9pvhsi3sft569bfa47b