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Anti-TNF Treatment Response in Rheumatoid Arthritis Patients Is Associated with Genetic Variation in the NLRP3-Inflammasome

OBJECTIVE: Many patients with rheumatoid arthritis (RA) benefit from tumor necrosis factor-α blocking treatment (anti-TNF), but about one third do not respond. The objective of this study was to replicate and extend previously found associations between anti-TNF treatment response and genetic variat...

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Detalles Bibliográficos
Autores principales:	Sode, Jacob, Vogel, Ulla, Bank, Steffen, Andersen, Paal Skytt, Thomsen, Marianne Kragh, Hetland, Merete Lund, Locht, Henning, Heegaard, Niels H. H., Andersen, Vibeke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072633/ https://www.ncbi.nlm.nih.gov/pubmed/24967817 http://dx.doi.org/10.1371/journal.pone.0100361

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