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Modeling Neutralization Kinetics of HIV by Broadly Neutralizing Monoclonal Antibodies in Genital Secretions Coating the Cervicovaginal Mucosa

Eliciting broadly neutralizing antibodies (bnAb) in cervicovaginal mucus (CVM) represents a promising “first line of defense” strategy to reduce vaginal HIV transmission. However, it remains unclear what levels of bnAb must be present in CVM to effectively reduce infection. We approached this comple...

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Detalles Bibliográficos
Autores principales:	McKinley, Scott A., Chen, Alex, Shi, Feng, Wang, Simi, Mucha, Peter J., Forest, M. Gregory, Lai, Samuel K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072659/ https://www.ncbi.nlm.nih.gov/pubmed/24967706 http://dx.doi.org/10.1371/journal.pone.0100598

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