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Mycobacteria Counteract a TLR-Mediated Nitrosative Defense Mechanism in a Zebrafish Infection Model
Pulmonary tuberculosis (TB), caused by the intracellular bacterial pathogen Mycobacterium tuberculosis (Mtb), is a major world health problem. The production of reactive nitrogen species (RNS) is a potent cytostatic and cytotoxic defense mechanism against intracellular pathogens. Nevertheless, the p...
Autores principales: | Elks, Philip M., van der Vaart, Michiel, van Hensbergen, Vincent, Schutz, Esther, Redd, Michael J., Murayama, Emi, Spaink, Herman P., Meijer, Annemarie H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072692/ https://www.ncbi.nlm.nih.gov/pubmed/24967596 http://dx.doi.org/10.1371/journal.pone.0100928 |
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