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Macrophage Depletion by Free Bisphosphonates and Zoledronate-Loaded Red Blood Cells
Bisphosphonates, besides being important drugs for the treatment of various bone diseases, could also be used to induce apoptosis in macrophage-like and cancer cells. However, their activity in vivo is limited by a short plasma half-life and rapid uptake within bone. Therefore, several delivery syst...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072741/ https://www.ncbi.nlm.nih.gov/pubmed/24968029 http://dx.doi.org/10.1371/journal.pone.0101260 |