Discovery of a Novel Compound with Anti-Venezuelan Equine Encephalitis Virus Activity That Targets the Nonstructural Protein 2

Alphaviruses present serious health threats as emerging and re-emerging viruses. Venezuelan equine encephalitis virus (VEEV), a New World alphavirus, can cause encephalitis in humans and horses, but there are no therapeutics for treatment. To date, compounds reported as anti-VEEV or anti-alphavirus...

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Detalles Bibliográficos
Autores principales: Chung, Dong-Hoon, Jonsson, Colleen B., Tower, Nichole A., Chu, Yong-Kyu, Sahin, Ergin, Golden, Jennifer E., Noah, James W., Schroeder, Chad E., Sotsky, Julie B., Sosa, Melinda I., Cramer, Daniel E., McKellip, Sara N., Rasmussen, Lynn, White, E. Lucile, Schmaljohn, Connie S., Julander, Justin G., Smith, Jeffrey M., Filone, Claire Marie, Connor, John H., Sakurai, Yasuteru, Davey, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072787/
https://www.ncbi.nlm.nih.gov/pubmed/24967809
http://dx.doi.org/10.1371/journal.ppat.1004213

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