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Natural solution to antibiotic resistance: bacteriophages ‘The Living Drugs’
Antibiotics have been a panacea in animal husbandry as well as in human therapy for decades. The huge amount of antibiotics used to induce the growth and protect the health of farm animals has lead to the evolution of bacteria that are resistant to the drug’s effects. Today, many researchers are wor...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072922/ https://www.ncbi.nlm.nih.gov/pubmed/24781265 http://dx.doi.org/10.1007/s11274-014-1655-7 |
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author | Jassim, Sabah A. A. Limoges, Richard G. |
author_facet | Jassim, Sabah A. A. Limoges, Richard G. |
author_sort | Jassim, Sabah A. A. |
collection | PubMed |
description | Antibiotics have been a panacea in animal husbandry as well as in human therapy for decades. The huge amount of antibiotics used to induce the growth and protect the health of farm animals has lead to the evolution of bacteria that are resistant to the drug’s effects. Today, many researchers are working with bacteriophages (phages) as an alternative to antibiotics in the control of pathogens for human therapy as well as prevention, biocontrol, and therapy in animal agriculture. Phage therapy and biocontrol have yet to fulfill their promise or potential, largely due to several key obstacles to their performance. Several suggestions are shared in order to point a direction for overcoming common obstacles in applied phage technology. The key to successful use of phages in modern scientific, farm, food processing and clinical applications is to understand the common obstacles as well as best practices and to develop answers that work in harmony with nature. |
format | Online Article Text |
id | pubmed-4072922 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-40729222014-07-25 Natural solution to antibiotic resistance: bacteriophages ‘The Living Drugs’ Jassim, Sabah A. A. Limoges, Richard G. World J Microbiol Biotechnol Review Antibiotics have been a panacea in animal husbandry as well as in human therapy for decades. The huge amount of antibiotics used to induce the growth and protect the health of farm animals has lead to the evolution of bacteria that are resistant to the drug’s effects. Today, many researchers are working with bacteriophages (phages) as an alternative to antibiotics in the control of pathogens for human therapy as well as prevention, biocontrol, and therapy in animal agriculture. Phage therapy and biocontrol have yet to fulfill their promise or potential, largely due to several key obstacles to their performance. Several suggestions are shared in order to point a direction for overcoming common obstacles in applied phage technology. The key to successful use of phages in modern scientific, farm, food processing and clinical applications is to understand the common obstacles as well as best practices and to develop answers that work in harmony with nature. Springer Netherlands 2014-04-30 2014 /pmc/articles/PMC4072922/ /pubmed/24781265 http://dx.doi.org/10.1007/s11274-014-1655-7 Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Review Jassim, Sabah A. A. Limoges, Richard G. Natural solution to antibiotic resistance: bacteriophages ‘The Living Drugs’ |
title | Natural solution to antibiotic resistance: bacteriophages ‘The Living Drugs’ |
title_full | Natural solution to antibiotic resistance: bacteriophages ‘The Living Drugs’ |
title_fullStr | Natural solution to antibiotic resistance: bacteriophages ‘The Living Drugs’ |
title_full_unstemmed | Natural solution to antibiotic resistance: bacteriophages ‘The Living Drugs’ |
title_short | Natural solution to antibiotic resistance: bacteriophages ‘The Living Drugs’ |
title_sort | natural solution to antibiotic resistance: bacteriophages ‘the living drugs’ |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072922/ https://www.ncbi.nlm.nih.gov/pubmed/24781265 http://dx.doi.org/10.1007/s11274-014-1655-7 |
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