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Contribution of genetic variation to transgenerational inheritance of DNA methylation

BACKGROUND: Despite the important role DNA methylation plays in transcriptional regulation, the transgenerational inheritance of DNA methylation is not well understood. The genetic heritability of DNA methylation has been estimated using twin pairs, although concern has been expressed whether the un...

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Detalles Bibliográficos
Autores principales:	McRae, Allan F, Powell, Joseph E, Henders, Anjali K, Bowdler, Lisa, Hemani, Gibran, Shah, Sonia, Painter, Jodie N, Martin, Nicholas G, Visscher, Peter M, Montgomery, Grant W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072933/ https://www.ncbi.nlm.nih.gov/pubmed/24887635 http://dx.doi.org/10.1186/gb-2014-15-5-r73

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