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PDE9A is expressed in the inner retina and contributes to the normal shape of the photopic ERG waveform

The ubiquitous second messenger cGMP is synthesized by guanylyl cyclase and hydrolyzed by phosphodiesterase (PDE). cGMP mediates numerous signaling pathways in multiple tissues. In the retina, cGMP regulates signaling in nearly every cell class including photoreceptors, bipolar cells, amacrine cells...

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Detalles Bibliográficos
Autores principales:	Dhingra, Anuradha, Tummala, Shanti R., Lyubarsky, Arkady, Vardi, Noga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073215/ https://www.ncbi.nlm.nih.gov/pubmed/25018695 http://dx.doi.org/10.3389/fnmol.2014.00060

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