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Zebrafish enpp1 mutants exhibit pathological mineralization, mimicking features of generalized arterial calcification of infancy (GACI) and pseudoxanthoma elasticum (PXE)
In recent years it has become clear that, mechanistically, biomineralization is a process that has to be actively inhibited as a default state. This inhibition must be released in a rigidly controlled manner in order for mineralization to occur in skeletal elements and teeth. A central aspect of thi...
Autores principales: | Apschner, Alexander, Huitema, Leonie F. A., Ponsioen, Bas, Peterson-Maduro, Josi, Schulte-Merker, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073271/ https://www.ncbi.nlm.nih.gov/pubmed/24906371 http://dx.doi.org/10.1242/dmm.015693 |
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