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Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer
The mechanisms through which cancer cells lock in altered transcriptional programs in support of metastasis remain largely unknown. Through integrative analysis of clinical breast cancer gene expression datasets, cell line models of breast cancer progression, and mutation data from cancer genome res...
Autores principales: | Vanharanta, Sakari, Marney, Christina B, Shu, Weiping, Valiente, Manuel, Zou, Yilong, Mele, Aldo, Darnell, Robert B, Massagué, Joan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073284/ https://www.ncbi.nlm.nih.gov/pubmed/24898756 http://dx.doi.org/10.7554/eLife.02734 |
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