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Granulocytic sarcoma in non-leukaemic child involving maxillary sinus with long term follow up: A rare case report

Granulocytic sarcoma (GS) is a rare extramedullary malignant tumor composed of immature myeloid cells. It is strongly associated with acute myeloid leukaemia, chronic myeloproliferative diseases. Occurrence of GS in the oral cavity is extremely uncommon. Present case reported an unusual occurrence o...

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Autores principales: Sharma, Aman, Singh, Harkanwal Preet, Gupta, Anish Ashok, Garg, Parveen, Moon, Ninad Joshirao, Chavan, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073472/
https://www.ncbi.nlm.nih.gov/pubmed/24987607
http://dx.doi.org/10.4103/2231-0746.133078
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author Sharma, Aman
Singh, Harkanwal Preet
Gupta, Anish Ashok
Garg, Parveen
Moon, Ninad Joshirao
Chavan, Rahul
author_facet Sharma, Aman
Singh, Harkanwal Preet
Gupta, Anish Ashok
Garg, Parveen
Moon, Ninad Joshirao
Chavan, Rahul
author_sort Sharma, Aman
collection PubMed
description Granulocytic sarcoma (GS) is a rare extramedullary malignant tumor composed of immature myeloid cells. It is strongly associated with acute myeloid leukaemia, chronic myeloproliferative diseases. Occurrence of GS in the oral cavity is extremely uncommon. Present case reported an unusual occurrence of GS without leukemia involving maxillary sinus of a child. The patient underwent chemotherapy followed by radiotherapy with complete remission. A long-term follow-up of the patient was carried without any evidence of recurrence with special focus on diagnostic difficulties. The present case highlights the perplexity in diagnosing such lesions with emphasis on the need of careful interpretation of all clinical, radiographic, histopathological and immunohistochemical details as it is one of the most frequently misdiagnosed disorder.
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spelling pubmed-40734722014-07-01 Granulocytic sarcoma in non-leukaemic child involving maxillary sinus with long term follow up: A rare case report Sharma, Aman Singh, Harkanwal Preet Gupta, Anish Ashok Garg, Parveen Moon, Ninad Joshirao Chavan, Rahul Ann Maxillofac Surg Case Report - Oncology Granulocytic sarcoma (GS) is a rare extramedullary malignant tumor composed of immature myeloid cells. It is strongly associated with acute myeloid leukaemia, chronic myeloproliferative diseases. Occurrence of GS in the oral cavity is extremely uncommon. Present case reported an unusual occurrence of GS without leukemia involving maxillary sinus of a child. The patient underwent chemotherapy followed by radiotherapy with complete remission. A long-term follow-up of the patient was carried without any evidence of recurrence with special focus on diagnostic difficulties. The present case highlights the perplexity in diagnosing such lesions with emphasis on the need of careful interpretation of all clinical, radiographic, histopathological and immunohistochemical details as it is one of the most frequently misdiagnosed disorder. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4073472/ /pubmed/24987607 http://dx.doi.org/10.4103/2231-0746.133078 Text en Copyright: © Annals of Maxillofacial Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report - Oncology
Sharma, Aman
Singh, Harkanwal Preet
Gupta, Anish Ashok
Garg, Parveen
Moon, Ninad Joshirao
Chavan, Rahul
Granulocytic sarcoma in non-leukaemic child involving maxillary sinus with long term follow up: A rare case report
title Granulocytic sarcoma in non-leukaemic child involving maxillary sinus with long term follow up: A rare case report
title_full Granulocytic sarcoma in non-leukaemic child involving maxillary sinus with long term follow up: A rare case report
title_fullStr Granulocytic sarcoma in non-leukaemic child involving maxillary sinus with long term follow up: A rare case report
title_full_unstemmed Granulocytic sarcoma in non-leukaemic child involving maxillary sinus with long term follow up: A rare case report
title_short Granulocytic sarcoma in non-leukaemic child involving maxillary sinus with long term follow up: A rare case report
title_sort granulocytic sarcoma in non-leukaemic child involving maxillary sinus with long term follow up: a rare case report
topic Case Report - Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073472/
https://www.ncbi.nlm.nih.gov/pubmed/24987607
http://dx.doi.org/10.4103/2231-0746.133078
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