Relationship between genome and epigenome - challenges and requirements for future research

Understanding the links between genetic, epigenetic and non-genetic factors throughout the lifespan and across generations and their role in disease susceptibility and disease progression offer entirely new avenues and solutions to major problems in our society. To overcome the numerous challenges,...

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Detalles Bibliográficos
Autores principales: Almouzni, Geneviève, Altucci, Lucia, Amati, Bruno, Ashley, Neil, Baulcombe, David, Beaujean, Nathalie, Bock, Christoph, Bongcam-Rudloff, Erik, Bousquet, Jean, Braun, Sigurd, Paillerets, Brigitte Bressac-de, Bussemakers, Marion, Clarke, Laura, Conesa, Ana, Estivill, Xavier, Fazeli, Alireza, Grgurević, Neža, Gut, Ivo, Heijmans, Bastiaan T, Hermouet, Sylvie, Houwing–Duistermaat, Jeanine, Iacobucci, Ilaria, Ilaš, Janez, Kandimalla, Raju, Krauss-Etschmann, Susanne, Lasko, Paul, Lehmann, Sören, Lindroth, Anders, Majdič, Gregor, Marcotte, Eric, Martinelli, Giovanni, Martinet, Nadine, Meyer, Eric, Miceli, Cristina, Mills, Ken, Moreno-Villanueva, Maria, Morvan, Ghislaine, Nickel, Dörthe, Niesler, Beate, Nowacki, Mariusz, Nowak, Jacek, Ossowski, Stephan, Pelizzola, Mattia, Pochet, Roland, Potočnik, Uroš, Radwanska, Magdalena, Raes, Jeroen, Rattray, Magnus, Robinson, Mark D, Roelen, Bernard, Sauer, Sascha, Schinzer, Dieter, Slagboom, Eline, Spector, Tim, Stunnenberg, Hendrik G, Tiligada, Ekaterini, Torres-Padilla, Maria-Elena, Tsonaka, Roula, Soom, Ann Van, Vidaković, Melita, Widschwendter, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073504/
https://www.ncbi.nlm.nih.gov/pubmed/24942464
http://dx.doi.org/10.1186/1471-2164-15-487
Descripción
Sumario:Understanding the links between genetic, epigenetic and non-genetic factors throughout the lifespan and across generations and their role in disease susceptibility and disease progression offer entirely new avenues and solutions to major problems in our society. To overcome the numerous challenges, we have come up with nine major conclusions to set the vision for future policies and research agendas at the European level.

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