Rapid onset of cardiomyopathy in STZ-induced female diabetic mice involves the downregulation of pro-survival Pim-1

BACKGROUND: Diabetic women are five times more likely to develop congestive heart failure compared with two fold for men. The underlying mechanism for this gender difference is not known. Here we investigate the molecular mechanisms responsible for this female disadvantage and attempt safeguarding c...

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Detalles Bibliográficos
Autores principales: Moore, Andrew, Shindikar, Amol, Fomison-Nurse, Ingrid, Riu, Federica, Munasinghe, Pujika E, Parshu Ram, Thrishila, Saxena, Pankaj, Coffey, Sean, Bunton, Richard W, Galvin, Ivor F, Williams, Michael JA, Emanueli, Costanza, Madeddu, Paolo, Katare, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073808/
https://www.ncbi.nlm.nih.gov/pubmed/24685144
http://dx.doi.org/10.1186/1475-2840-13-68

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