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High Resolution Imaging Study of Interactions between the 37 kDa/67 kDa Laminin Receptor and APP, Beta-Secretase and Gamma-Secretase in Alzheimer's Disease

Alzheimer's disease (AD) is the most prevalent form of dementia affecting the elderly. Neurodegeneration is caused by the amyloid beta (Aβ) peptide which is generated from the sequential proteolytic cleavage of the Amyloid Precursor Protein (APP) by the β– and γ- secretases. Previous reports re...

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Detalles Bibliográficos
Autores principales: Jovanovic, Katarina, Loos, Ben, Da Costa Dias, Bianca, Penny, Clement, Weiss, Stefan F. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074076/
https://www.ncbi.nlm.nih.gov/pubmed/24972054
http://dx.doi.org/10.1371/journal.pone.0100373

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