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Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()()
BACKGROUND: It is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement. METHOD: Death registration data analysis (US, England & Wales (E&W)—1972–2009). RESULTS: CF median ag...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074348/ https://www.ncbi.nlm.nih.gov/pubmed/24418187 http://dx.doi.org/10.1016/j.jcf.2013.12.002 |
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author | Hurley, Matthew N. McKeever, Tricia M. Prayle, Andrew P. Fogarty, Andrew W. Smyth, Alan R. |
author_facet | Hurley, Matthew N. McKeever, Tricia M. Prayle, Andrew P. Fogarty, Andrew W. Smyth, Alan R. |
author_sort | Hurley, Matthew N. |
collection | PubMed |
description | BACKGROUND: It is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement. METHOD: Death registration data analysis (US, England & Wales (E&W)—1972–2009). RESULTS: CF median age of death is higher in US than E&W and greater for males, opposite to that of death from all causes. CF median age of death has increased by 0.543 life years per year (E&W, US combined (95% confidence interval 0.506, 0.582)). The difference in median age at death between those dying from all causes and CF decreased in both territories. CF median age of death for males is greater than for females in both territories. This gap has not narrowed. CONCLUSION: The median age of death of people with CF is improving more rapidly than that of the general population in US and E&W. |
format | Online Article Text |
id | pubmed-4074348 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-40743482014-07-07 Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()() Hurley, Matthew N. McKeever, Tricia M. Prayle, Andrew P. Fogarty, Andrew W. Smyth, Alan R. J Cyst Fibros Original Article BACKGROUND: It is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement. METHOD: Death registration data analysis (US, England & Wales (E&W)—1972–2009). RESULTS: CF median age of death is higher in US than E&W and greater for males, opposite to that of death from all causes. CF median age of death has increased by 0.543 life years per year (E&W, US combined (95% confidence interval 0.506, 0.582)). The difference in median age at death between those dying from all causes and CF decreased in both territories. CF median age of death for males is greater than for females in both territories. This gap has not narrowed. CONCLUSION: The median age of death of people with CF is improving more rapidly than that of the general population in US and E&W. Elsevier 2014-07 /pmc/articles/PMC4074348/ /pubmed/24418187 http://dx.doi.org/10.1016/j.jcf.2013.12.002 Text en © 2013 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved. https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use. |
spellingShingle | Original Article Hurley, Matthew N. McKeever, Tricia M. Prayle, Andrew P. Fogarty, Andrew W. Smyth, Alan R. Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()() |
title | Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()() |
title_full | Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()() |
title_fullStr | Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()() |
title_full_unstemmed | Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()() |
title_short | Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()() |
title_sort | rate of improvement of cf life expectancy exceeds that of general population—observational death registration study()() |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074348/ https://www.ncbi.nlm.nih.gov/pubmed/24418187 http://dx.doi.org/10.1016/j.jcf.2013.12.002 |
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