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Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()()

BACKGROUND: It is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement. METHOD: Death registration data analysis (US, England & Wales (E&W)—1972–2009). RESULTS: CF median ag...

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Autores principales: Hurley, Matthew N., McKeever, Tricia M., Prayle, Andrew P., Fogarty, Andrew W., Smyth, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074348/
https://www.ncbi.nlm.nih.gov/pubmed/24418187
http://dx.doi.org/10.1016/j.jcf.2013.12.002
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author Hurley, Matthew N.
McKeever, Tricia M.
Prayle, Andrew P.
Fogarty, Andrew W.
Smyth, Alan R.
author_facet Hurley, Matthew N.
McKeever, Tricia M.
Prayle, Andrew P.
Fogarty, Andrew W.
Smyth, Alan R.
author_sort Hurley, Matthew N.
collection PubMed
description BACKGROUND: It is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement. METHOD: Death registration data analysis (US, England & Wales (E&W)—1972–2009). RESULTS: CF median age of death is higher in US than E&W and greater for males, opposite to that of death from all causes. CF median age of death has increased by 0.543 life years per year (E&W, US combined (95% confidence interval 0.506, 0.582)). The difference in median age at death between those dying from all causes and CF decreased in both territories. CF median age of death for males is greater than for females in both territories. This gap has not narrowed. CONCLUSION: The median age of death of people with CF is improving more rapidly than that of the general population in US and E&W.
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spelling pubmed-40743482014-07-07 Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()() Hurley, Matthew N. McKeever, Tricia M. Prayle, Andrew P. Fogarty, Andrew W. Smyth, Alan R. J Cyst Fibros Original Article BACKGROUND: It is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement. METHOD: Death registration data analysis (US, England & Wales (E&W)—1972–2009). RESULTS: CF median age of death is higher in US than E&W and greater for males, opposite to that of death from all causes. CF median age of death has increased by 0.543 life years per year (E&W, US combined (95% confidence interval 0.506, 0.582)). The difference in median age at death between those dying from all causes and CF decreased in both territories. CF median age of death for males is greater than for females in both territories. This gap has not narrowed. CONCLUSION: The median age of death of people with CF is improving more rapidly than that of the general population in US and E&W. Elsevier 2014-07 /pmc/articles/PMC4074348/ /pubmed/24418187 http://dx.doi.org/10.1016/j.jcf.2013.12.002 Text en © 2013 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved. https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.
spellingShingle Original Article
Hurley, Matthew N.
McKeever, Tricia M.
Prayle, Andrew P.
Fogarty, Andrew W.
Smyth, Alan R.
Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()()
title Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()()
title_full Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()()
title_fullStr Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()()
title_full_unstemmed Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()()
title_short Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study()()
title_sort rate of improvement of cf life expectancy exceeds that of general population—observational death registration study()()
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074348/
https://www.ncbi.nlm.nih.gov/pubmed/24418187
http://dx.doi.org/10.1016/j.jcf.2013.12.002
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