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The genetic basis for inactivation of Wnt pathway in human osteosarcoma
BACKGROUND: Osteosarcoma is a highly genetically unstable tumor with poor prognosis. We performed microarray-based comparative genomic hybridization (aCGH), transcriptome sequencing (RNA-seq), and pathway analysis to gain a systemic view of the pathway alterations of osteosarcoma. METHODS: aCGH expe...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074405/ https://www.ncbi.nlm.nih.gov/pubmed/24942472 http://dx.doi.org/10.1186/1471-2407-14-450 |