Atg6/UVRAG/Vps34-Containing Lipid Kinase Complex Is Required for Receptor Downregulation through Endolysosomal Degradation and Epithelial Polarity during Drosophila Wing Development

Atg6 (Beclin 1 in mammals) is a core component of the Vps34 PI3K (III) complex, which promotes multiple vesicle trafficking pathways. Atg6 and Vps34 form two distinct PI3K (III) complexes in yeast and mammalian cells, either with Atg14 or with UVRAG. The functions of these two complexes are not enti...

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Detalles Bibliográficos
Autores principales: Lőrincz, Péter, Lakatos, Zsolt, Maruzs, Tamás, Szatmári, Zsuzsanna, Kis, Viktor, Sass, Miklós
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074780/
https://www.ncbi.nlm.nih.gov/pubmed/25006588
http://dx.doi.org/10.1155/2014/851349

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