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HE4 expression is associated with hormonal elements and mediated by importin-dependent nuclear translocation

Antiestrogens including tamoxifen and fulvestrant have been evaluated as chemotherapeutics for ovarian cancer, particularly in cases of platinum resistant disease. Human epididymis protein 4 (HE4) is highly overexpressed in women with ovarian cancer and overexpression of HE4 has been found to correl...

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Detalles Bibliográficos
Autores principales:	Lokich, Elizabeth, Singh, Rakesh K., Han, Alex, Romano, Nicole, Yano, Naohiro, Kim, Kyukwang, Moore, Richard G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074789/ https://www.ncbi.nlm.nih.gov/pubmed/24975515 http://dx.doi.org/10.1038/srep05500

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