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Critical Role of Aberrant Angiogenesis in the Development of Tumor Hypoxia and Associated Radioresistance

Newly formed microvessels in most solid tumors show an abnormal morphology and thus do not fulfil the metabolic demands of the growing tumor mass. Due to the chaotic and heterogeneous tumor microcirculation, a hostile tumor microenvironment develops, that is characterized inter alia by local hypoxia...

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Detalles Bibliográficos
Autores principales:	Multhoff, Gabriele, Radons, Jürgen, Vaupel, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074805/ https://www.ncbi.nlm.nih.gov/pubmed/24717239 http://dx.doi.org/10.3390/cancers6020813

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