Cargando…

Mechanisms of Cancer Induction by Tobacco-Specific NNK and NNN

Tobacco use is a major public health problem worldwide. Tobacco-related cancers cause millions of deaths annually. Although several tobacco agents play a role in the development of tumors, the potent effects of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N'-nitrosonornicotine (NNN)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xue, Jiaping, Yang, Suping, Seng, Seyha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074821/ https://www.ncbi.nlm.nih.gov/pubmed/24830349 http://dx.doi.org/10.3390/cancers6021138

Ejemplares similares

UHPLC-MS/MS method for the simultaneous determination of nicotine and tobacco-specific nitrosamines NNN and NNK for use in preclinical studies
por: Meikopoulos, Thomas, et al.
Publicado: (2022)

Assessment of the Exposure to NNN in the Plasma of Smokeless Tobacco Users
por: Pluym, Nikola, et al.
Publicado: (2022)

NNK, a Tobacco-Specific Carcinogen, Inhibits the Expression of Lysyl Oxidase, a Tumor Suppressor
por: Cheng, Guang, et al.
Publicado: (2014)

Cigarette smoke modulates PC3 prostate cancer cell migration by altering adhesion molecules and the extracellular matrix
por: YANG, SUPING, et al.
Publicado: (2015)

Metabolic Activation and Carcinogenesis of Tobacco-Specific Nitrosamine N’-Nitrosonornicotine (NNN): A Density Function Theory and Molecular Docking Study
por: Fan, Tengjiao, et al.
Publicado: (2019)

NNN Nucleon Decay and Neutrino Detector Workshop
por: Collective
Publicado: (2000)

The Role of Nitrosamine (NNK) in Breast Cancer Carcinogenesis
por: Gankhuyag, Nomundelger, et al.
Publicado: (2017)

Cigarette smoke induces nuclear translocation of heme oxygenase 1 (HO-1) in prostate cancer cells: Nuclear HO-1 promotes vascular endothelial growth factor secretion
por: BIRRANE, GABRIEL, et al.
Publicado: (2013)

NNK-Induced Lung Tumors: A Review of Animal Model
por: Zheng, Hua-Chuan, et al.
Publicado: (2011)

Halide exchange studies of novel Pd(ii) NNN-pincer complexes
por: Kuyuldar, Seher, et al.
Publicado: (2019)

Evidence for the reaction $\pi ^{-}p \to$ nnn at 40 GeV/c
por: Apel, W D
Publicado: (1975)

Evaluation of tobacco specific nitrosamines exposure by quantification of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human hair of non-smokers
por: Pérez-Ortuño, Raúl, et al.
Publicado: (2016)

Investigation of Precise Molecular Mechanistic Action of Tobacco-Associated Carcinogen ‘NNK’ Induced Carcinogenesis: A System Biology Approach
por: Anukriti,, et al.
Publicado: (2019)

Efficient additive-free formic acid dehydrogenation with a NNN–ruthenium complex
por: Knörr, Pascal, et al.
Publicado: (2023)

Synthesis, Characterization, and Catalytic Application of Palladium Complexes Containing Indolyl-NNN-Type Ligands
por: Lo, Pang-Chia, et al.
Publicado: (2021)

Comparative Functional Genomics Analysis of NNK Tobacco-Carcinogen Induced Lung Adenocarcinoma Development in Gprc5a-Knockout Mice
por: Fujimoto, Junya, et al.
Publicado: (2010)

The tobacco carcinogen NNK drives accumulation of DNMT1 at the GR promoter thereby reducing GR expression in untransformed lung fibroblasts
por: Taylor, Kerryn M., et al.
Publicado: (2018)

Enhancing Ethylene Polymerization of NNN-Cobalt(II) Precatalysts Adorned with a Fluoro-substituent
por: Bariashir, Chantsalnyam, et al.
Publicado: (2021)

The Effect of NNK, A Tobacco Smoke Carcinogen, on the miRNA and Mismatch DNA Repair Expression Profiles in Lung and Head and Neck Squamous Cancer Cells
por: Doukas, Sotirios G., et al.
Publicado: (2020)

Bcl2 Family Functions as Signaling Target in Nicotine-/NNK-Induced Survival of Human Lung Cancer Cells
por: Deng, Xingming
Publicado: (2014)

NNK from tobacco smoking enhances pancreatic cancer cell stemness and chemoresistance by creating a β2AR‐Akt feedback loop that activates autophagy
por: Chen, Xin, et al.
Publicado: (2022)

The tobacco-specific carcinogen NNK induces pulmonary tumorigenesis via nAChR/Src/STAT3-mediated activation of the renin-angiotensin system and IGF-1R signaling
por: Boo, Hye-Jin, et al.
Publicado: (2023)

Unveiling the Electronic Structure of the Bi(+1)/Bi(+3) Redox Couple on NCN and NNN Pincer Complexes
por: Gimferrer, Martí, et al.
Publicado: (2021)

Palladium complexes containing NNN pincer type ligands and their activities in Suzuki-Miyaura cross coupling reaction
por: Keskin, Ebru, et al.
Publicado: (2023)

The Effect of Tobacco Smoke N-Nitrosamines, NNK and NDEA, and Nicotine, on DNA Mismatch Repair Mechanism and miRNA Markers, in Hypopharyngeal Squamous Cell Carcinoma: An In Vivo Model and Clinical Evidence
por: Doukas, Sotirios G., et al.
Publicado: (2022)

Crystal structures of a novel NNN pincer ligand and its dinuclear titanium(IV) alkoxide pincer complex
por: Pedziwiatr, Jakub, et al.
Publicado: (2017)

miR-124 Inhibits Lung Tumorigenesis Induced by K-ras Mutation and NNK
por: Jin, Hua, et al.
Publicado: (2017)

Targeting CD36 determines nicotine derivative NNK-induced lung adenocarcinoma carcinogenesis
por: Li, Ming-Yue, et al.
Publicado: (2023)

Identification of a long non-coding RNA NR_026689 associated with lung carcinogenesis induced by NNK
por: Wu, Jianjun, et al.
Publicado: (2016)

Synthesis, Reactivity, and Catalytic Transfer Hydrogenation Activity of Ruthenium Complexes Bearing NNN Tridentate Ligands: Influence of the Secondary Coordination Sphere
por: Shi, Jing, et al.
Publicado: (2017)

Highly Linear Polyethylenes Achieved Using Thermo-Stable and Efficient Cobalt Precatalysts Bearing Carbocyclic-Fused NNN-Pincer Ligand
por: Guo, Jingjing, et al.
Publicado: (2019)

Early and delayed intervention with Rapamycin prevents NNK-induced lung adenocarcinoma in A/J mice
por: PATLOLLA, JAGAN M.R., et al.
Publicado: (2015)

Chimeric RNA RRM2-C2orf48 plays an oncogenic role in the development of NNK-induced lung cancer
por: Zhou, Jiazhen, et al.
Publicado: (2022)

Magnetic dummy template molecularly imprinted particles functionalized with dendritic nanoclusters for selective enrichment and determination of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in tobacco products
por: Zheng, Yani, et al.
Publicado: (2023)

β(2)-Adrenogenic signaling regulates NNK-induced pancreatic cancer progression via upregulation of HIF-1α
por: Zhang, Dong, et al.
Publicado: (2015)

Emergence of a New [NNN] Pincer Ligand via Si−H Bond Activation and β‐Hydride Abstraction at Tetravalent Cerium
por: Werner, Daniel, et al.
Publicado: (2020)

Unraveling the Effect of Aromatic Groups in Mn(I)NNN Pincer Complexes on Carbon Dioxide Activation Using Density Functional Study
por: Parmar, Saurabh Vinod, et al.
Publicado: (2021)

XB130 translocation to microfilamentous structures mediates NNK-induced migration of human bronchial epithelial cells
por: Wu, Qifei, et al.
Publicado: (2015)

The permissive role of TCTP in PM(2.5)/NNK-induced epithelial–mesenchymal transition in lung cells
por: Liu, Li-Zhong, et al.
Publicado: (2020)

Identifying Frequently Used NANDA-I Nursing Diagnoses, NOC Outcomes, NIC Interventions, and NNN Linkages for Nursing Home Residents in Korea
por: Shin, Juh Hyun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hnqonka45qs3lepbns3n2f4ml6