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Performance of HLA allele prediction methods in African Americans for class II genes HLA-DRB1, −DQB1, and –DPB1
BACKGROUND: The expense of human leukocyte antigen (HLA) allele genotyping has motivated the development of imputation methods that use dense single nucleotide polymorphism (SNP) genotype data and the region’s haplotype structure, but the performance of these methods in admixed populations (such as...
Autores principales: | Levin, Albert M, Adrianto, Indra, Datta, Indrani, Iannuzzi, Michael C, Trudeau, Sheri, McKeigue, Paul, Montgomery, Courtney G, Rybicki, Benjamin A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074844/ https://www.ncbi.nlm.nih.gov/pubmed/24935557 http://dx.doi.org/10.1186/1471-2156-15-72 |
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