Engineered RNase P Ribozymes Effectively Inhibit Human Cytomegalovirus Gene Expression and Replication

RNase P ribozyme can be engineered to be a sequence-specific gene-targeting agent with promising application in both basic research and clinical settings. By using an in vitro selection system, we have previously generated RNase P ribozyme variants that have better catalytic activity in cleaving an...

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Detalles Bibliográficos
Autores principales: Yang, Zhu, Vu, Gia-Phong, Qian, Hua, Chen, Yuan-Chuan, Wang, Yu, Reeves, Michael, Zen, Ke, Liu, Fenyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074932/
https://www.ncbi.nlm.nih.gov/pubmed/24932966
http://dx.doi.org/10.3390/v6062376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074932/
https://www.ncbi.nlm.nih.gov/pubmed/24932966
http://dx.doi.org/10.3390/v6062376

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