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Ibuprofen Protects Ventilator-Induced Lung Injury by Downregulating Rho-Kinase Activity in Rats

Background. Ventilator-induced lung injury-(VILI-) induced endothelial permeability is regulated through the Rho-dependent signaling pathway. Ibuprofen inhibits Rho activation in animal models of spinal-cord injury and Alzheimer's disease. The study aims to investigate ibuprofen effects on high...

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Detalles Bibliográficos
Autores principales:	Huang, Liang-Ti, Lin, Chien-Huang, Chou, Hsiu-Chu, Chen, Chung-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075182/ https://www.ncbi.nlm.nih.gov/pubmed/25019086 http://dx.doi.org/10.1155/2014/749097

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