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Doxycycline use in patients with lymphangioleiomyomatosis: biomarkers and pulmonary function response ,
OBJECTIVE: To assess blockade of matrix metalloproteinase (MMP)-2 and MMP-9, as well as the variation in FEV(1), in patients with lymphangioleiomyomatosis (LAM) treated with doxycycline (a known MMP inhibitor) for 12 months. METHODS: An open-label, single-arm, interventional clinical trial in which...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Sociedade Brasileira de Pneumologia e Tisiologia
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075801/ https://www.ncbi.nlm.nih.gov/pubmed/23503480 http://dx.doi.org/10.1590/S1806-37132013000100002 |