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Characteristics of tuberculosis in the state of Minas Gerais, Brazil: 2002-2009

OBJECTIVE: To analyze the profile of tuberculosis cases reported between 2002 and 2009 in the state of Minas Gerais, Brazil, according to sociodemographic, clinical, and laboratory characteristics, as well as to comorbidities and mortality. METHODS: This was a descriptive, epidemiological study base...

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Autores principales: Augusto, Cláudio José, Carvalho, Wânia da Silva, Gonçalves, Alan Douglas, Ceccato, Maria das Graças Braga, de Miranda, Silvana Spindola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Pneumologia e Tisiologia 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075843/
https://www.ncbi.nlm.nih.gov/pubmed/23857684
http://dx.doi.org/10.1590/S1806-37132013000300013
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author Augusto, Cláudio José
Carvalho, Wânia da Silva
Gonçalves, Alan Douglas
Ceccato, Maria das Graças Braga
de Miranda, Silvana Spindola
author_facet Augusto, Cláudio José
Carvalho, Wânia da Silva
Gonçalves, Alan Douglas
Ceccato, Maria das Graças Braga
de Miranda, Silvana Spindola
author_sort Augusto, Cláudio José
collection PubMed
description OBJECTIVE: To analyze the profile of tuberculosis cases reported between 2002 and 2009 in the state of Minas Gerais, Brazil, according to sociodemographic, clinical, and laboratory characteristics, as well as to comorbidities and mortality. METHODS: This was a descriptive, epidemiological study based on data obtained from the Brazilian Case Registry Database and the Brazilian Mortality Database for the 2002-2009 period. RESULTS: There were 47,285 reported cases of tuberculosis, corresponding to a mean incidence of 22.3/100,000 population. The individuals diagnosed with tuberculosis were predominantly in the 20- to 49-year age bracket and male (62.4% and 67.0%, respectively). Individuals with a low level of education accounted for 18.5% of the cases. New cases, cases of recurrence, and cases of retreatment accounted for 83.7%, 5.7%, 5.7%, respectively. The rates of cure and treatment noncompliance were 66.2% and 11.2%, respectively; multidrug-resistant tuberculosis was identified in 0.2% of the cases; and the mortality rate was 12.9%. The directly observed treatment, short-course (DOTS) strategy was applied in 21.8% of the cases. Sputum smear microscopy and culture were performed in only 73.9% and 12.9% of the cases, respectively. Chest X-rays were performed in 90.5% of the cases. Pulmonary tuberculosis was the predominant form (in 83.9%). Comorbidity with alcoholism, HIV infection, and diabetes mellitus were identified in 17.2%, 8.3%, and 3.8%, respectively. CONCLUSIONS: During the study period, the numbers of new cases, cases of treatment noncompliance, and deaths were high, comorbidities were common, and there was a failure to perform adequately basic tests for the diagnosis of tuberculosis. Multidisciplinary approaches, expanded use of the DOTS strategy, better knowledge of the distribution of tuberculosis, and improvements in the databases are needed in order to achieve better control of the disease in the state of Minas Gerais.
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spelling pubmed-40758432014-07-16 Characteristics of tuberculosis in the state of Minas Gerais, Brazil: 2002-2009 Augusto, Cláudio José Carvalho, Wânia da Silva Gonçalves, Alan Douglas Ceccato, Maria das Graças Braga de Miranda, Silvana Spindola J Bras Pneumol Original Articles OBJECTIVE: To analyze the profile of tuberculosis cases reported between 2002 and 2009 in the state of Minas Gerais, Brazil, according to sociodemographic, clinical, and laboratory characteristics, as well as to comorbidities and mortality. METHODS: This was a descriptive, epidemiological study based on data obtained from the Brazilian Case Registry Database and the Brazilian Mortality Database for the 2002-2009 period. RESULTS: There were 47,285 reported cases of tuberculosis, corresponding to a mean incidence of 22.3/100,000 population. The individuals diagnosed with tuberculosis were predominantly in the 20- to 49-year age bracket and male (62.4% and 67.0%, respectively). Individuals with a low level of education accounted for 18.5% of the cases. New cases, cases of recurrence, and cases of retreatment accounted for 83.7%, 5.7%, 5.7%, respectively. The rates of cure and treatment noncompliance were 66.2% and 11.2%, respectively; multidrug-resistant tuberculosis was identified in 0.2% of the cases; and the mortality rate was 12.9%. The directly observed treatment, short-course (DOTS) strategy was applied in 21.8% of the cases. Sputum smear microscopy and culture were performed in only 73.9% and 12.9% of the cases, respectively. Chest X-rays were performed in 90.5% of the cases. Pulmonary tuberculosis was the predominant form (in 83.9%). Comorbidity with alcoholism, HIV infection, and diabetes mellitus were identified in 17.2%, 8.3%, and 3.8%, respectively. CONCLUSIONS: During the study period, the numbers of new cases, cases of treatment noncompliance, and deaths were high, comorbidities were common, and there was a failure to perform adequately basic tests for the diagnosis of tuberculosis. Multidisciplinary approaches, expanded use of the DOTS strategy, better knowledge of the distribution of tuberculosis, and improvements in the databases are needed in order to achieve better control of the disease in the state of Minas Gerais. Sociedade Brasileira de Pneumologia e Tisiologia 2013 /pmc/articles/PMC4075843/ /pubmed/23857684 http://dx.doi.org/10.1590/S1806-37132013000300013 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Augusto, Cláudio José
Carvalho, Wânia da Silva
Gonçalves, Alan Douglas
Ceccato, Maria das Graças Braga
de Miranda, Silvana Spindola
Characteristics of tuberculosis in the state of Minas Gerais, Brazil: 2002-2009
title Characteristics of tuberculosis in the state of Minas Gerais, Brazil: 2002-2009
title_full Characteristics of tuberculosis in the state of Minas Gerais, Brazil: 2002-2009
title_fullStr Characteristics of tuberculosis in the state of Minas Gerais, Brazil: 2002-2009
title_full_unstemmed Characteristics of tuberculosis in the state of Minas Gerais, Brazil: 2002-2009
title_short Characteristics of tuberculosis in the state of Minas Gerais, Brazil: 2002-2009
title_sort characteristics of tuberculosis in the state of minas gerais, brazil: 2002-2009
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075843/
https://www.ncbi.nlm.nih.gov/pubmed/23857684
http://dx.doi.org/10.1590/S1806-37132013000300013
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