Cargando…

Performance comparison between the mycobacteria growth indicator tube system and Löwenstein-Jensen medium in the routine detection of Mycobacterium tuberculosis at public health care facilities in Rio de Janeiro, Brazil: preliminary results of a pragmatic clinical trial

In view of the fact that the World Health Organization has recommended the use of the mycobacteria growth indicator tube (MGIT) 960 system for the diagnosis of tuberculosis and that there is as yet no evidence regarding the clinical impact of its use in health care systems, we conducted a pragmatic...

Descripción completa

Detalles Bibliográficos
Autores principales: Moreira, Adriana da Silva Rezende, Huf, Gisele, Vieira, Maria Armanda, Fonseca, Leila, Ricks, Monica, Kritski, Afrânio Lineu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Pneumologia e Tisiologia 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075853/
https://www.ncbi.nlm.nih.gov/pubmed/23857683
http://dx.doi.org/10.1590/S1806-37132013000300014
_version_ 1782323406284259328
author Moreira, Adriana da Silva Rezende
Huf, Gisele
Vieira, Maria Armanda
Fonseca, Leila
Ricks, Monica
Kritski, Afrânio Lineu
author_facet Moreira, Adriana da Silva Rezende
Huf, Gisele
Vieira, Maria Armanda
Fonseca, Leila
Ricks, Monica
Kritski, Afrânio Lineu
author_sort Moreira, Adriana da Silva Rezende
collection PubMed
description In view of the fact that the World Health Organization has recommended the use of the mycobacteria growth indicator tube (MGIT) 960 system for the diagnosis of tuberculosis and that there is as yet no evidence regarding the clinical impact of its use in health care systems, we conducted a pragmatic clinical trial to evaluate the clinical performance and cost-effectiveness of the use of MGIT 960 at two health care facilities in the city of Rio de Janeiro, Brazil, where the incidence of tuberculosis is high. Here, we summarize the methodology and preliminary results of the trial. (ISRCTN.org Identifier: ISRCTN79888843 [http://isrctn.org/])
format Online
Article
Text
id pubmed-4075853
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Sociedade Brasileira de Pneumologia e Tisiologia
record_format MEDLINE/PubMed
spelling pubmed-40758532014-07-16 Performance comparison between the mycobacteria growth indicator tube system and Löwenstein-Jensen medium in the routine detection of Mycobacterium tuberculosis at public health care facilities in Rio de Janeiro, Brazil: preliminary results of a pragmatic clinical trial Moreira, Adriana da Silva Rezende Huf, Gisele Vieira, Maria Armanda Fonseca, Leila Ricks, Monica Kritski, Afrânio Lineu J Bras Pneumol Brief Communication In view of the fact that the World Health Organization has recommended the use of the mycobacteria growth indicator tube (MGIT) 960 system for the diagnosis of tuberculosis and that there is as yet no evidence regarding the clinical impact of its use in health care systems, we conducted a pragmatic clinical trial to evaluate the clinical performance and cost-effectiveness of the use of MGIT 960 at two health care facilities in the city of Rio de Janeiro, Brazil, where the incidence of tuberculosis is high. Here, we summarize the methodology and preliminary results of the trial. (ISRCTN.org Identifier: ISRCTN79888843 [http://isrctn.org/]) Sociedade Brasileira de Pneumologia e Tisiologia 2013 /pmc/articles/PMC4075853/ /pubmed/23857683 http://dx.doi.org/10.1590/S1806-37132013000300014 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
Moreira, Adriana da Silva Rezende
Huf, Gisele
Vieira, Maria Armanda
Fonseca, Leila
Ricks, Monica
Kritski, Afrânio Lineu
Performance comparison between the mycobacteria growth indicator tube system and Löwenstein-Jensen medium in the routine detection of Mycobacterium tuberculosis at public health care facilities in Rio de Janeiro, Brazil: preliminary results of a pragmatic clinical trial
title Performance comparison between the mycobacteria growth indicator tube system and Löwenstein-Jensen medium in the routine detection of Mycobacterium tuberculosis at public health care facilities in Rio de Janeiro, Brazil: preliminary results of a pragmatic clinical trial
title_full Performance comparison between the mycobacteria growth indicator tube system and Löwenstein-Jensen medium in the routine detection of Mycobacterium tuberculosis at public health care facilities in Rio de Janeiro, Brazil: preliminary results of a pragmatic clinical trial
title_fullStr Performance comparison between the mycobacteria growth indicator tube system and Löwenstein-Jensen medium in the routine detection of Mycobacterium tuberculosis at public health care facilities in Rio de Janeiro, Brazil: preliminary results of a pragmatic clinical trial
title_full_unstemmed Performance comparison between the mycobacteria growth indicator tube system and Löwenstein-Jensen medium in the routine detection of Mycobacterium tuberculosis at public health care facilities in Rio de Janeiro, Brazil: preliminary results of a pragmatic clinical trial
title_short Performance comparison between the mycobacteria growth indicator tube system and Löwenstein-Jensen medium in the routine detection of Mycobacterium tuberculosis at public health care facilities in Rio de Janeiro, Brazil: preliminary results of a pragmatic clinical trial
title_sort performance comparison between the mycobacteria growth indicator tube system and löwenstein-jensen medium in the routine detection of mycobacterium tuberculosis at public health care facilities in rio de janeiro, brazil: preliminary results of a pragmatic clinical trial
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075853/
https://www.ncbi.nlm.nih.gov/pubmed/23857683
http://dx.doi.org/10.1590/S1806-37132013000300014
work_keys_str_mv AT moreiraadrianadasilvarezende performancecomparisonbetweenthemycobacteriagrowthindicatortubesystemandlowensteinjensenmediumintheroutinedetectionofmycobacteriumtuberculosisatpublichealthcarefacilitiesinriodejaneirobrazilpreliminaryresultsofapragmaticclinicaltrial
AT hufgisele performancecomparisonbetweenthemycobacteriagrowthindicatortubesystemandlowensteinjensenmediumintheroutinedetectionofmycobacteriumtuberculosisatpublichealthcarefacilitiesinriodejaneirobrazilpreliminaryresultsofapragmaticclinicaltrial
AT vieiramariaarmanda performancecomparisonbetweenthemycobacteriagrowthindicatortubesystemandlowensteinjensenmediumintheroutinedetectionofmycobacteriumtuberculosisatpublichealthcarefacilitiesinriodejaneirobrazilpreliminaryresultsofapragmaticclinicaltrial
AT fonsecaleila performancecomparisonbetweenthemycobacteriagrowthindicatortubesystemandlowensteinjensenmediumintheroutinedetectionofmycobacteriumtuberculosisatpublichealthcarefacilitiesinriodejaneirobrazilpreliminaryresultsofapragmaticclinicaltrial
AT ricksmonica performancecomparisonbetweenthemycobacteriagrowthindicatortubesystemandlowensteinjensenmediumintheroutinedetectionofmycobacteriumtuberculosisatpublichealthcarefacilitiesinriodejaneirobrazilpreliminaryresultsofapragmaticclinicaltrial
AT kritskiafraniolineu performancecomparisonbetweenthemycobacteriagrowthindicatortubesystemandlowensteinjensenmediumintheroutinedetectionofmycobacteriumtuberculosisatpublichealthcarefacilitiesinriodejaneirobrazilpreliminaryresultsofapragmaticclinicaltrial