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Hsp70 - a biomarker for tumor detection and monitoring of outcome of radiation therapy in patients with squamous cell carcinoma of the head and neck

BACKGROUND: Tumor but not normal cells frequently overexpress heat shock protein 70 (Hsp70) and present it on their cell surface (mHsp70) from where it can be actively released. Therefore, membrane (mHsp70) and soluble Hsp70 (sHsp70) were investigated as potential tumor biomarkers and for monitoring...

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Detalles Bibliográficos
Autores principales: Gehrmann, Mathias, Specht, Hanno M, Bayer, Christine, Brandstetter, Markus, Chizzali, Barbara, Duma, Marciana, Breuninger, Stephanie, Hube, Kathrin, Lehnerer, Sophie, van Phi, Valerie, Sage, Eva, Schmid, Thomas E, Sedelmayr, Michael, Schilling, Daniela, Sievert, Wolfgang, Stangl, Stefan, Multhoff, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075935/
https://www.ncbi.nlm.nih.gov/pubmed/24912482
http://dx.doi.org/10.1186/1748-717X-9-131