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Hsp70 - a biomarker for tumor detection and monitoring of outcome of radiation therapy in patients with squamous cell carcinoma of the head and neck
BACKGROUND: Tumor but not normal cells frequently overexpress heat shock protein 70 (Hsp70) and present it on their cell surface (mHsp70) from where it can be actively released. Therefore, membrane (mHsp70) and soluble Hsp70 (sHsp70) were investigated as potential tumor biomarkers and for monitoring...
Autores principales: | Gehrmann, Mathias, Specht, Hanno M, Bayer, Christine, Brandstetter, Markus, Chizzali, Barbara, Duma, Marciana, Breuninger, Stephanie, Hube, Kathrin, Lehnerer, Sophie, van Phi, Valerie, Sage, Eva, Schmid, Thomas E, Sedelmayr, Michael, Schilling, Daniela, Sievert, Wolfgang, Stangl, Stefan, Multhoff, Gabriele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075935/ https://www.ncbi.nlm.nih.gov/pubmed/24912482 http://dx.doi.org/10.1186/1748-717X-9-131 |
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