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Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors

BACKGROUND: The TLR7/8 agonist 3M-052 and the TLR9 agonist CpG ODN both trigger innate immune responses that support the induction of tumor-specific immunity. Previous studies showed that these agonists used individually could improve the survival of mice challenged with small tumors but were of lim...

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Detalles Bibliográficos
Autores principales:	Zhao, By Gan, Vasilakos, John P, Tross, Debra, Smirnov, Dmitri, Klinman, Dennis M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075973/ https://www.ncbi.nlm.nih.gov/pubmed/24982761 http://dx.doi.org/10.1186/2051-1426-2-12

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