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Aggregation Behavior of Chemically Synthesized, Full-Length Huntingtin Exon1

[Image: see text] Repeat length disease thresholds vary among the 10 expanded polyglutamine (polyQ) repeat diseases, from about 20 to about 50 glutamine residues. The unique amino acid sequences flanking the polyQ segment are thought to contribute to these repeat length thresholds. The specific port...

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Detalles Bibliográficos
Autores principales:	Sahoo, Bankanidhi, Singer, David, Kodali, Ravindra, Zuchner, Thole, Wetzel, Ronald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075985/ https://www.ncbi.nlm.nih.gov/pubmed/24921664 http://dx.doi.org/10.1021/bi500300c

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