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Nonaggregated α-Synuclein Influences SNARE-Dependent Vesicle Docking via Membrane Binding
[Image: see text] α-Synuclein (α-Syn), a major component of Lewy body that is considered as the hallmark of Parkinson’s disease (PD), has been implicated in neuroexocytosis. Overexpression of α-Syn decreases the neurotransmitter release. However, the mechanism by which α-Syn buildup inhibits the neu...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075992/ https://www.ncbi.nlm.nih.gov/pubmed/24884175 http://dx.doi.org/10.1021/bi5002536 |