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Copper-Catalyzed [(18)F]Fluorination of (Mesityl)(aryl)iodonium Salts

[Image: see text] A practical, rapid, and highly regioselective Cu-catalyzed radiofluorination of (mesityl)(aryl)iodonium salts is described. This protocol utilizes [(18)F]KF to access (18)F-labeled electron-rich, -neutral, and -deficient aryl fluorides under a single set of mild conditions. This me...

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Detalles Bibliográficos
Autores principales: Ichiishi, Naoko, Brooks, Allen F., Topczewski, Joseph J., Rodnick, Melissa E., Sanford, Melanie S., Scott, Peter J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076000/
https://www.ncbi.nlm.nih.gov/pubmed/24890658
http://dx.doi.org/10.1021/ol501243g