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Stereocontrolled Synthesis of Bicyclic Sulfamides via Pd-Catalyzed Alkene Carboamination Reactions. Control of 1,3-Asymmetric Induction by Manipulating Mechanistic Pathways

[Image: see text] A new annulation strategy for the synthesis of trans-bicyclic sulfamides is described. The Pd-catalyzed alkene carboamination reactions of 2-allyl and cis-2,5-diallyl pyrrolidinyl sulfamides with aryl and alkenyl triflates afford the fused bicyclic compounds in good yields and with...

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Detalles Bibliográficos
Autores principales: Babij, Nicholas R., McKenna, Grace M., Fornwald, Ryan M., Wolfe, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076003/
https://www.ncbi.nlm.nih.gov/pubmed/24916343
http://dx.doi.org/10.1021/ol5015976