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Identification and Characterization of an Allosteric Inhibitory Site on Dihydropteroate Synthase

[Image: see text] The declining effectiveness of current antibiotics due to the emergence of resistant bacterial strains dictates a pressing need for novel classes of antimicrobial therapies, preferably against molecular sites other than those in which resistance mutations have developed. Dihydropte...

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Detalles Bibliográficos
Autores principales:	Hammoudeh, Dalia I., Daté, Mihir, Yun, Mi-Kyung, Zhang, Weixing, Boyd, Vincent A., Viacava Follis, Ariele, Griffith, Elizabeth, Lee, Richard E., Bashford, Donald, White, Stephen W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076017/ https://www.ncbi.nlm.nih.gov/pubmed/24650357 http://dx.doi.org/10.1021/cb500038g

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