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RANK receptor oligomerisation in the regulation of NFκB signalling

The interaction of receptor activator of NFκB (RANK), a member of the tumour necrosis factor receptor superfamily, with RANK ligand is crucial for the formation, function and survival of osteoclasts. The role of the cytoplasmic oligomerisation domain (pre-ligand assembly domain; PLAD or ‘IVVY’ motif...

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Detalles Bibliográficos
Autores principales: Das, S, Sepahi, I, Duthie, A, Clark, S, Crockett, J C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076115/
https://www.ncbi.nlm.nih.gov/pubmed/24859969
http://dx.doi.org/10.1530/JME-14-0077