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Crystallization Scale Preparation of a Stable GPCR Signaling Complex between Constitutively Active Rhodopsin and G-Protein
The activation of the G-protein transducin (Gt) by rhodopsin (Rho) has been intensively studied for several decades. It is the best understood example of GPCR activation mechanism and serves as a template for other GPCRs. The structure of the Rho/G protein complex, which is transiently formed during...
Autores principales: | Maeda, Shoji, Sun, Dawei, Singhal, Ankita, Foggetta, Marcello, Schmid, Georg, Standfuss, Joerg, Hennig, Michael, Dawson, Roger J. P., Veprintsev, Dmitry B., Schertler, Gebhard F. X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076187/ https://www.ncbi.nlm.nih.gov/pubmed/24979345 http://dx.doi.org/10.1371/journal.pone.0098714 |
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