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Using beta binomials to estimate classification uncertainty for ensemble models

BACKGROUND: Quantitative structure-activity (QSAR) models have enormous potential for reducing drug discovery and development costs as well as the need for animal testing. Great strides have been made in estimating their overall reliability, but to fully realize that potential, researchers and regul...

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Detalles Bibliográficos
Autores principales: Clark, Robert D, Liang, Wenkel, Lee, Adam C, Lawless, Michael S, Fraczkiewicz, Robert, Waldman, Marvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076254/
https://www.ncbi.nlm.nih.gov/pubmed/24987464
http://dx.doi.org/10.1186/1758-2946-6-34