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Using beta binomials to estimate classification uncertainty for ensemble models
BACKGROUND: Quantitative structure-activity (QSAR) models have enormous potential for reducing drug discovery and development costs as well as the need for animal testing. Great strides have been made in estimating their overall reliability, but to fully realize that potential, researchers and regul...
Autores principales: | Clark, Robert D, Liang, Wenkel, Lee, Adam C, Lawless, Michael S, Fraczkiewicz, Robert, Waldman, Marvin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076254/ https://www.ncbi.nlm.nih.gov/pubmed/24987464 http://dx.doi.org/10.1186/1758-2946-6-34 |
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