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Therapeutic Effect of TSG-6 Engineered iPSC-Derived MSCs on Experimental Periodontitis in Rats: A Pilot Study

BACKGROUND: We derived mesenchymal stem cells (MSCs) from rat induced pluripotent stem cells (iPSCs) and transduced them with tumor necrosis factor alpha-stimulated gene-6 (TSG-6), to test whether TSG-6 overexpression would boost the therapeutic effects of iPSC-derived MSCs in experimental periodont...

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Detalles Bibliográficos
Autores principales: Yang, Heng, Aprecio, Raydolfo M., Zhou, Xiaodong, Wang, Qi, Zhang, Wu, Ding, Yi, Li, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076279/
https://www.ncbi.nlm.nih.gov/pubmed/24979372
http://dx.doi.org/10.1371/journal.pone.0100285