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Systematic Characterization and Comparative Analysis of the Rabbit Immunoglobulin Repertoire
Rabbits have been used extensively as a model system for the elucidation of the mechanism of immunoglobulin diversification and for the production of antibodies. We employed Next Generation Sequencing to analyze Ig germline V and J gene usage, CDR3 length and amino acid composition, and gene convers...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076286/ https://www.ncbi.nlm.nih.gov/pubmed/24978027 http://dx.doi.org/10.1371/journal.pone.0101322 |