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Systematic Fine-Mapping of Association with BMI and Type 2 Diabetes at the FTO Locus by Integrating Results from Multiple Ethnic Groups
BACKGROUND/OBJECTIVE: The 16q12.2 locus in the first intron of FTO has been robustly associated with body mass index (BMI) and type 2 diabetes in genome-wide association studies (GWAS). To improve the resolution of fine-scale mapping at FTO, we performed a systematic approach consisting of two parts...
Autores principales: | Akiyama, Koichi, Takeuchi, Fumihiko, Isono, Masato, Chakrawarthy, Sureka, Nguyen, Quang Ngoc, Wen, Wanqing, Yamamoto, Ken, Katsuya, Tomohiro, Kasturiratne, Anuradhani, Pham, Son Thai, Zheng, Wei, Matsushita, Yumi, Kishimoto, Miyako, Do, Loi Doan, Shu, Xiao-Ou, Wickremasinghe, Ananda R., Kajio, Hiroshi, Kato, Norihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076329/ https://www.ncbi.nlm.nih.gov/pubmed/24978468 http://dx.doi.org/10.1371/journal.pone.0101329 |
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