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Systematic Fine-Mapping of Association with BMI and Type 2 Diabetes at the FTO Locus by Integrating Results from Multiple Ethnic Groups

BACKGROUND/OBJECTIVE: The 16q12.2 locus in the first intron of FTO has been robustly associated with body mass index (BMI) and type 2 diabetes in genome-wide association studies (GWAS). To improve the resolution of fine-scale mapping at FTO, we performed a systematic approach consisting of two parts...

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Detalles Bibliográficos
Autores principales: Akiyama, Koichi, Takeuchi, Fumihiko, Isono, Masato, Chakrawarthy, Sureka, Nguyen, Quang Ngoc, Wen, Wanqing, Yamamoto, Ken, Katsuya, Tomohiro, Kasturiratne, Anuradhani, Pham, Son Thai, Zheng, Wei, Matsushita, Yumi, Kishimoto, Miyako, Do, Loi Doan, Shu, Xiao-Ou, Wickremasinghe, Ananda R., Kajio, Hiroshi, Kato, Norihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076329/
https://www.ncbi.nlm.nih.gov/pubmed/24978468
http://dx.doi.org/10.1371/journal.pone.0101329

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