Cargando…

Mirtazapine has a therapeutic potency in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mice model of Parkinson’s disease

BACKGROUND: Mirtazapine, a noradrenergic and specific serotonergic antidepressant (NaSSA), shows multiple pharmacological actions such as inhibiting presynaptic α(2) noradrenaline receptor (NAR) and selectively activating 5-hydroxytriptamine (5-HT) 1A receptor (5-HT(1A)R). Mirtazapine was also repor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kadoguchi, Naoto, Okabe, Shinji, Yamamura, Yukio, Shono, Misaki, Fukano, Tatsuya, Tanabe, Akie, Yokoyama, Hironori, Kasahara, Jiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076436/ https://www.ncbi.nlm.nih.gov/pubmed/24965042 http://dx.doi.org/10.1186/1471-2202-15-79

Ejemplares similares

Microglia reaction on the neurotoxic effect of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) in the nigrostriatal pathway in mice
por: Czlonkowska, A., et al.
Publicado: (1994)

Resveratrol attenuates oxidative stress and improves behaviour in 1 -methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) challenged mice
por: Anandhan, Annadurai, et al.
Publicado: (2010)

Pain perception in acute model mice of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
por: Park, Jihye, et al.
Publicado: (2015)

Ganoderma lucidum Modulates Inflammatory Responses following 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Administration in Mice
por: Ren, Zhili, et al.
Publicado: (2022)

Dispersed Activity during Passive Movement in the Globus Pallidus of the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Treated Primate
por: Erez, Yaara, et al.
Publicado: (2011)

SIRT2 enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via apoptotic pathway
por: Liu, Lei, et al.
Publicado: (2014)

Dietary curcumin supplementation attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in C57BL mice
por: He, Xi-Jun, et al.
Publicado: (2015)

Acute Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) or Paraquat on Core Temperature in C57BL/6J Mice
por: Jiao, Yun, et al.
Publicado: (2015)

A Mouse Model of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Induced Parkinson Disease Shows that 2-Aminoquinoline Targets JNK Phosphorylation
por: Zhu, Meie, et al.
Publicado: (2020)

Characterization of neurobehavioral pattern in a zebrafish 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced model: A 96-hour behavioral study
por: Razali, Khairiah, et al.
Publicado: (2022)

Synergistic effects of influenza and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) can be eliminated by the use of influenza therapeutics: experimental evidence for the multi-hit hypothesis
por: Sadasivan, Shankar, et al.
Publicado: (2017)

Anodal transcranial direct current stimulation prevents methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity by modulating autophagy in an in vivo mouse model of Parkinson’s disease
por: Lee, Sang-Bin, et al.
Publicado: (2018)

e-Cadherin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson Disease
por: Cataldi, Samuela, et al.
Publicado: (2016)

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
por: Cho, Kyoung-in, et al.
Publicado: (2012)

Dopamine signaling negatively regulates striatal phosphorylation of Cdk5 at tyrosine 15 in mice
por: Yamamura, Yukio, et al.
Publicado: (2013)

Anti-parkinsonian effects of octacosanol in 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-treated mice☆
por: Wang, Tao, et al.
Publicado: (2012)

Glucagon-Like Peptide-1 Receptor Agonist Ameliorates 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Neurotoxicity Through Enhancing Mitophagy Flux and Reducing α-Synuclein and Oxidative Stress
por: Lin, Tsu-Kung, et al.
Publicado: (2021)

Overexpression of Parkin Ameliorates Dopaminergic Neurodegeneration Induced by 1- Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice
por: Bian, Minjuan, et al.
Publicado: (2012)

Acute Morphine Treatments Alleviate Tremor in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Monkeys
por: Yan, Ting, et al.
Publicado: (2014)

Therapeutic effects of paeonol on methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid-induced Parkinson's disease in mice
por: Shi, Xiaojin, et al.
Publicado: (2016)

Transient dystonia correlates with parkinsonism after 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine in nonhuman primates
por: Norris, S. A., et al.
Publicado: (2023)

A novel tyrosine kinase inhibitor AMN107 (nilotinib) normalizes striatal motor behaviors in a mouse model of Parkinson’s disease
por: Tanabe, Akie, et al.
Publicado: (2014)

Dopamine receptor 3 might be an essential molecule in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
por: Chen, Yan, et al.
Publicado: (2013)

Neuroprotective potential of Quercetin in combination with piperine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
por: Singh, Shamsher, et al.
Publicado: (2017)

Isopropyl 1-benzoyl-4-benzoyloxy-2,6-diphenyl-1,2,3,6-tetrahydropyridine-3-carboxylate
por: Govindan, E., et al.
Publicado: (2014)

Korean Red Ginseng Enhances Neurogenesis in the Subventricular Zone of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Mice
por: Ryu, Sun, et al.
Publicado: (2018)

Comparison of the effect of rotenone and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on inducing chronic Parkinson's disease in mouse models
por: Zhang, Jing, et al.
Publicado: (2022)

Neuroprotective Effects of a Cholecystokinin Analogue in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Parkinson’s Disease Mouse Model
por: Zhang, Zijuan, et al.
Publicado: (2022)

Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
por: Mounsey, Ross B., et al.
Publicado: (2015)

Selenium reduces nociceptive response in acute 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced neurotoxicity
por: Abolarin, Patrick Oluwole, et al.
Publicado: (2021)

Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease
por: Fujita, Kyota, et al.
Publicado: (2009)

Dangguijakyak-San Protects against 1-Methyl-4-phenyl-1,2,3,6,-tetrahydropyridine-Induced Neuronal Damage via Anti-Inflammatory Action
por: Hwang, Deok-Sang, et al.
Publicado: (2013)

Effects of L-arginine pre-treatment in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson’s diseases in Balb/c mice
por: Hami, Javad, et al.
Publicado: (2015)

Neuroprotective Effect of Schisandra Chinensis on Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Parkinsonian Syndrome in C57BL/6 Mice
por: Li, Chi-Lin, et al.
Publicado: (2019)

Rho kinase II interference by small hairpin RNA ameliorates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice
por: Zhang, Qiong, et al.
Publicado: (2016)

Differential Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on Motor Behavior and Dopamine Levels at Brain Regions in Three Different Mouse Strains
por: Lee, Keun-Sung, et al.
Publicado: (2013)

Metabolite Profile Resulting from the Activation/Inactivation of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 2-Methyltetrahydro-β-carboline by Oxidative Enzymes
por: Herraiz, Tomás, et al.
Publicado: (2013)

A peroxisome proliferator-activated receptor-δ agonist provides neuroprotection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson’s disease
por: Martin, H.L., et al.
Publicado: (2013)

Beneficial effects of L-arginine on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neuronal degeneration in substantia nigra of Balb/c mice
por: Hami, Javad, et al.
Publicado: (2016)

Effect of treadmill exercise on catalepsy and the expression of the BDNF gene in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine -induced Parkinson in male NMRI mice
por: Nikokalam Nazif, Neda, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8qdhv6rml58lb3celerho1ahlf