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Phosphodiesterase-3 inhibitor (cilostazol) attenuates oxidative stress-induced mitochondrial dysfunction in the heart

BACKGROUND: Cilostazol is a type 3 phosphodiesterase inhibitor which has been previously demonstrated to prevent the occurrence of tachyarrhythmia and improve defibrillation efficacy. However, the mechanism for this beneficial effect is still unclear. Since cardiac mitochondria have been shown to pl...

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Detalles Bibliográficos
Autores principales: Chattipakorn, Siriporn C., Thummasorn, Savitree, Sanit, Jantira, Chattipakorn, Nipon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076456/
https://www.ncbi.nlm.nih.gov/pubmed/25009566
http://dx.doi.org/10.3969/j.issn.1671-5411.2014.02.014