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Calculation of exact p-values when SNPs are tested using multiple genetic models

BACKGROUND: Several methods have been proposed to account for multiple comparisons in genetic association studies. However, investigators typically test each of the SNPs using multiple genetic models. Association testing using the Cochran-Armitage test for trend assuming an additive, dominant, or re...

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Detalles Bibliográficos
Autores principales:	Talluri, Rajesh, Wang, Jian, Shete, Sanjay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076502/ https://www.ncbi.nlm.nih.gov/pubmed/24950707 http://dx.doi.org/10.1186/1471-2156-15-75

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